Cardiovascular Diseases

The Leading Cause of Death Worldwide

Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 25% of deaths in the U.S. and 31% of deaths worldwide. Nearly 18 million people die each year from cardiovascular disease (CVD)-related events including heart attack and stroke.

Despite current standard of care treatments, residual risk of heart attack, stroke and death remains high in patients with CVD. Developing new treatments  is a challenge due to the heterogeneity of the patient population and the resulting variation in response to treatment.

Scientific advances in precision medicine now allow for a patient’s genetic profile to be considered during the development of new treatments. This targeted approach identifies individual patients who may benefit from a particular treatment, based on a specific genetic subtype,

DalCor is developing dalcetrapib, the first  precision medicine to reduce cardiovascular risk above and beyond the current standard of care in patients who carry the ADCY9 rs1967309 AA genotype.